{"id":1969,"date":"2026-05-27T18:49:29","date_gmt":"2026-05-27T11:49:29","guid":{"rendered":"https:\/\/meelf.biz\/tpc\/?p=1969"},"modified":"2026-05-30T10:53:23","modified_gmt":"2026-05-30T03:53:23","slug":"why-skin-ages-intrinsic-vs-extrinsic-aging","status":"publish","type":"post","link":"https:\/\/meelf.biz\/tpc\/why-skin-ages-intrinsic-vs-extrinsic-aging\/","title":{"rendered":"\u3010\u7f8e\u5bb9\u533b\u7642\u306e\u57fa\u790e\u77e5\u8b58\u3011\u306a\u305c\u808c\u306f\u8001\u5316\u3059\u308b\u306e\u304b\uff1f"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1969\" class=\"elementor elementor-1969\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2d6d0a8 e-flex e-con-boxed e-con e-parent\" data-id=\"2d6d0a8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63ba8d3 elementor-widget elementor-widget-heading\" data-id=\"63ba8d3\" 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data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u201cIntrinsic Aging\u201d\u3068\u201cExtrinsic Aging\u201d\u304b\u3089\u7406\u89e3\u3059\u308b\u672c\u5f53\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc77a04 elementor-widget elementor-widget-text-editor\" data-id=\"dc77a04\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"83\" data-end=\"149\">\u300c\u6700\u8fd1\u3001\u9854\u304c\u75b2\u308c\u3066\u898b\u3048\u308b\u300d<br data-start=\"96\" data-end=\"99\" \/>\u300c\u540c\u5e74\u4ee3\u306a\u306e\u306b\u3001\u808c\u5e74\u9f62\u306b\u5dee\u3092\u611f\u3058\u308b\u300d<br data-start=\"117\" data-end=\"120\" 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elementor-size-default\">\u201c\u82e5\u3044\u808c\u201d\u3068\u201c\u8001\u3051\u305f\u808c\u201d\u306e\u9055\u3044\u3068\u306f\uff1f<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e9291a elementor-widget elementor-widget-text-editor\" data-id=\"3e9291a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"886\" data-end=\"931\">\u300c\u82e5\u3044\u808c\uff1d\u30b7\u30ef\u304c\u306a\u3044\u808c\u300d\u3068\u601d\u308f\u308c\u304c\u3061\u3067\u3059\u304c\u3001\u5b9f\u969b\u306b\u306f\u201c\u808c\u69cb\u9020\u306e\u8cea\u201d\u304c\u5927\u304d\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p data-start=\"933\" data-end=\"939\">\u82e5\u3044\u808c\u3067\u306f\u3001<\/p>\n<ul data-start=\"941\" data-end=\"986\">\n<li data-section-id=\"qcsrct\" data-start=\"941\" data-end=\"954\">\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u6574\u3063\u3066\u3044\u308b<\/li>\n<li 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data-end=\"1044\">\u304c\u81ea\u7136\u306b\u611f\u3058\u3089\u308c\u308b\u306e\u3067\u3059 \u3002<\/p>\n<p data-start=\"1046\" data-end=\"1069\">\u3057\u304b\u3057<span style=\"font-family: 'Noto Sans JP', sans-serif; font-size: 15px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: 0.1px;\">\u5185\u56e0\u6027\u8001\u5316<\/span>\u304c\u9032\u3080\u3068\u3001<\/p>\n<ul data-start=\"1071\" data-end=\"1109\">\n<li data-section-id=\"9netj6\" data-start=\"1071\" data-end=\"1079\">\u808c\u304c\u8584\u304f\u306a\u308b<\/li>\n<li data-section-id=\"1kgwljr\" data-start=\"1080\" data-end=\"1090\">\u4e7e\u71e5\u3057\u3084\u3059\u304f\u306a\u308b<\/li>\n<li data-section-id=\"1bbednj\" data-start=\"1091\" data-end=\"1101\">\u56de\u5fa9\u529b\u304c\u4f4e\u4e0b\u3059\u308b<\/li>\n<li data-section-id=\"5a1ddd\" data-start=\"1102\" data-end=\"1109\">\u30cf\u30ea\u304c\u6e1b\u308b<\/li>\n<\/ul>\n<p data-start=\"1111\" data-end=\"1124\">\u3068\u3044\u3063\u305f\u5909\u5316\u304c\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n<p data-start=\"1126\" data-end=\"1156\">\u300c\u5bdd\u4e0d\u8db3\u304c\u9854\u306b\u51fa\u3084\u3059\u304f\u306a\u3063\u305f\u300d<br data-start=\"1141\" data-end=\"1144\" \/>\u300c\u30cb\u30ad\u30d3\u8de1\u304c\u6cbb\u308a\u306b\u304f\u3044\u300d<\/p>\n<p data-start=\"1158\" data-end=\"1177\">\u3068\u3044\u3046\u5909\u5316\u3082\u3001\u8001\u5316\u30b5\u30a4\u30f3\u306e\u3072\u3068\u3064\u3067\u3059\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-99f5798 elementor-widget elementor-widget-heading\" data-id=\"99f5798\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Extrinsic Aging\uff08\u5916\u56e0\u6027\u8001\u5316\uff09\u3068\u306f\uff1f<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f39a98c elementor-widget elementor-widget-text-editor\" data-id=\"f39a98c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h3 data-section-id=\"47cnax\" data-start=\"1214\" data-end=\"1237\">\u808c\u8001\u5316\u3092\u52a0\u901f\u3055\u305b\u308b\u201c\u751f\u6d3b\u7fd2\u6163\u3068\u74b0\u5883\u201d <img decoding=\"async\" class=\"emoji\" role=\"img\" draggable=\"false\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/17.0.2\/svg\/2600.svg\" alt=\"\u2600\" \/><\/h3>\n<p data-start=\"1239\" data-end=\"1294\">\u5185\u56e0\u6027\u8001\u5316\u304c\u81ea\u7136\u8001\u5316\u306a\u3089\u3001\u5916\u56e0\u6027\u8001\u5316\u306f\u201c\u5916\u90e8\u30c0\u30e1\u30fc\u30b8\u306b\u3088\u308b\u8001\u5316\u201d\u3067\u3059\u3002<\/p>\n<p data-start=\"1296\" data-end=\"1326\">\u3053\u3061\u3089\u306f\u3001\u65e5\u3005\u306e\u7fd2\u6163\u306b\u3088\u3063\u3066\u9032\u884c\u30b9\u30d4\u30fc\u30c9\u304c\u5927\u304d\u304f\u5909\u308f\u308a\u307e\u3059\u3002<\/p>\n<p data-start=\"1328\" data-end=\"1334\">\u4e3b\u306a\u539f\u56e0\u306f\u3001<\/p>\n<ul data-start=\"1336\" data-end=\"1387\">\n<li data-section-id=\"1q5wsv\" data-start=\"1336\" data-end=\"1341\">\u7d2b\u5916\u7dda<\/li>\n<li data-section-id=\"175tzuk\" data-start=\"1342\" data-end=\"1349\">PM2.5<\/li>\n<li data-section-id=\"1p57gkx\" data-start=\"1350\" data-end=\"1356\">\u5927\u6c17\u6c5a\u67d3<\/li>\n<li data-section-id=\"1labf87\" data-start=\"1357\" data-end=\"1363\">\u7761\u7720\u4e0d\u8db3<\/li>\n<li data-section-id=\"1bm1a98\" data-start=\"1364\" data-end=\"1370\">\u30b9\u30c8\u30ec\u30b9<\/li>\n<li data-section-id=\"yhw5yy\" data-start=\"1371\" data-end=\"1375\">\u55ab\u7159<\/li>\n<li data-section-id=\"yi6cp4\" data-start=\"1376\" data-end=\"1380\">\u98f2\u9152<\/li>\n<li data-section-id=\"1ny8dic\" data-start=\"1381\" data-end=\"1387\">\u6162\u6027\u708e\u75c7<\/li>\n<\/ul>\n<p data-start=\"1389\" data-end=\"1394\">\u306a\u3069\u3067\u3059\u3002<\/p>\n<p data-start=\"1396\" data-end=\"1415\">\u4e2d\u3067\u3082\u6700\u5927\u306e\u539f\u56e0\u306f\u300c\u7d2b\u5916\u7dda\uff08UV\uff09\u300d\u3002<\/p>\n<p data-start=\"1417\" data-end=\"1456\">\u76ae\u819a\u79d1\u3067\u306f\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u8001\u5316\u3092\u300cPhotoaging\uff08\u5149\u8001\u5316\uff09\u300d\u3068\u547c\u3073\u307e\u3059 <img decoding=\"async\" class=\"emoji\" role=\"img\" draggable=\"false\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/17.0.2\/svg\/2600.svg\" alt=\"\u2600\" \/><\/p>\n<p data-start=\"1458\" data-end=\"1467\">\u7d2b\u5916\u7dda\u306f\u808c\u5185\u90e8\u3067\u3001<\/p>\n<ul data-start=\"1469\" data-end=\"1498\">\n<li data-section-id=\"1nc2qh8\" data-start=\"1469\" data-end=\"1475\">\u6d3b\u6027\u9178\u7d20<\/li>\n<li data-section-id=\"yhptep\" data-start=\"1476\" data-end=\"1480\">\u708e\u75c7<\/li>\n<li data-section-id=\"d6poot\" data-start=\"1481\" data-end=\"1498\">MMPs\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u89e3\u9175\u7d20\uff09<\/li>\n<\/ul>\n<p data-start=\"1500\" data-end=\"1521\">\u3092\u5897\u3084\u3057\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3084ECM\u3092\u7834\u58ca\u3057\u307e\u3059\u3002<\/p>\n<p data-start=\"1523\" data-end=\"1528\">\u305d\u306e\u7d50\u679c\u3001<\/p>\n<ul data-start=\"1530\" data-end=\"1560\">\n<li data-section-id=\"yhdwcw\" data-start=\"1530\" data-end=\"1534\">\u30b7\u30ef<\/li>\n<li data-section-id=\"1gerab\" data-start=\"1535\" data-end=\"1540\">\u305f\u308b\u307f<\/li>\n<li data-section-id=\"1twxfv3\" data-start=\"1541\" data-end=\"1548\">\u6bdb\u7a74\u306e\u958b\u304d<\/li>\n<li data-section-id=\"yhdwdc\" data-start=\"1549\" data-end=\"1553\">\u30b7\u30df<\/li>\n<li data-section-id=\"1bi1i08\" data-start=\"1554\" data-end=\"1560\">\u30cf\u30ea\u4f4e\u4e0b<\/li>\n<\/ul>\n<p data-start=\"1562\" data-end=\"1572\">\u304c\u9032\u884c\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<p data-start=\"1574\" data-end=\"1612\">\u3064\u307e\u308a\u3001\u201c\u808c\u5e74\u9f62\u306e\u5dee\u201d\u306f\u5916\u56e0\u6027\u8001\u5316\u306e\u5dee\u3068\u3082\u8a00\u3048\u308b\u306e\u3067\u3059\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fbe9c9e elementor-widget elementor-widget-heading\" data-id=\"fbe9c9e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u82e5\u3044\u306e\u306b\u8001\u3051\u3066\u898b\u3048\u308b\u300c\u65e9\u671f\u8001\u5316\u300d\u3068\u306f\uff1f<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fee099 elementor-widget elementor-widget-text-editor\" data-id=\"8fee099\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"1642\" data-end=\"1651\">\u6700\u8fd1\u306f20\u4ee3\u3067\u3082\u3001<\/p>\n<ul data-start=\"1653\" data-end=\"1676\">\n<li data-section-id=\"1vgc8g\" data-start=\"1653\" data-end=\"1658\">\u5c0f\u30b8\u30ef<\/li>\n<li data-section-id=\"yhq84n\" data-start=\"1659\" data-end=\"1663\">\u6bdb\u7a74<\/li>\n<li data-section-id=\"1gefxd\" data-start=\"1664\" data-end=\"1669\">\u304f\u3059\u307f<\/li>\n<li data-section-id=\"1bi1i08\" data-start=\"1670\" data-end=\"1676\">\u30cf\u30ea\u4f4e\u4e0b<\/li>\n<\/ul>\n<p data-start=\"1678\" data-end=\"1691\">\u3092\u611f\u3058\u308b\u65b9\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p data-start=\"1693\" data-end=\"1726\">\u3053\u308c\u306f\u300cPremature Aging\uff08\u65e9\u671f\u8001\u5316\uff09\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002<\/p>\n<p data-start=\"1728\" data-end=\"1738\">\u539f\u56e0\u3068\u3057\u3066\u591a\u3044\u306e\u304c\u3001<\/p>\n<ul data-start=\"1740\" data-end=\"1782\">\n<li data-section-id=\"1labf87\" data-start=\"1740\" data-end=\"1746\">\u7761\u7720\u4e0d\u8db3<\/li>\n<li data-section-id=\"15qvu67\" data-start=\"1747\" data-end=\"1755\">\u5f37\u3044\u30b9\u30c8\u30ec\u30b9<\/li>\n<li data-section-id=\"1li0hts\" data-start=\"1756\" data-end=\"1762\">\u7cd6\u8cea\u904e\u591a<\/li>\n<li data-section-id=\"ac5pai\" data-start=\"1763\" data-end=\"1771\">\u6162\u6027\u7684\u306a\u708e\u75c7<\/li>\n<li data-section-id=\"brlo08\" data-start=\"1772\" data-end=\"1782\">\u904e\u5270\u306a\u30b9\u30ad\u30f3\u30b1\u30a2<\/li>\n<\/ul>\n<p data-start=\"1784\" data-end=\"1789\">\u306a\u3069\u3067\u3059\u3002<\/p>\n<p data-start=\"1791\" data-end=\"1827\">\u7279\u306b\u6162\u6027\u7684\u306a\u708e\u75c7\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3084ECM\u3092\u52a3\u5316\u3055\u305b\u3001\u808c\u8001\u5316\u3092\u52a0\u901f\u3055\u305b\u307e\u3059\u3002<\/p>\n<p data-start=\"1829\" data-end=\"1871\">\u201c\u75b2\u308c\u9854\u201d\u306f\u3001\u5358\u306a\u308b\u898b\u305f\u76ee\u3067\u306f\u306a\u304f\u3001\u808c\u5185\u90e8\u306e\u708e\u75c7\u30b5\u30a4\u30f3\u3067\u3042\u308b\u3053\u3068\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d3c309 elementor-widget elementor-widget-heading\" data-id=\"3d3c309\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u30b9\u30c8\u30ec\u30b9\u306f\u672c\u5f53\u306b\u808c\u3092\u8001\u5316\u3055\u305b\u308b\uff1f<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ca8fca elementor-widget elementor-widget-text-editor\" data-id=\"3ca8fca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"1901\" data-end=\"1912\">\u7b54\u3048\u306f\u300cYES\u300d\u3067\u3059\u3002<\/p>\n<p data-start=\"1914\" data-end=\"1949\">\u30b9\u30c8\u30ec\u30b9\u304c\u7d9a\u304f\u3068\u3001\u201c\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u201d\u3068\u3044\u3046\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u304c\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n<p data-start=\"1951\" data-end=\"1955\">\u3059\u308b\u3068\u3001<\/p>\n<ul data-start=\"1957\" data-end=\"1995\">\n<li data-section-id=\"pfnaif\" data-start=\"1957\" data-end=\"1966\">\u30d0\u30ea\u30a2\u6a5f\u80fd\u4f4e\u4e0b<\/li>\n<li data-section-id=\"29v1oa\" data-start=\"1967\" data-end=\"1972\">\u808c\u8352\u308c<\/li>\n<li data-section-id=\"yhptep\" data-start=\"1973\" data-end=\"1977\">\u708e\u75c7<\/li>\n<li data-section-id=\"10ixy2y\" data-start=\"1978\" data-end=\"1987\">\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u89e3<\/li>\n<li data-section-id=\"dsmd7l\" data-start=\"1988\" data-end=\"1995\">\u56de\u5fa9\u529b\u4f4e\u4e0b<\/li>\n<\/ul>\n<p data-start=\"1997\" data-end=\"2009\">\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p data-start=\"2011\" data-end=\"2016\">\u305d\u306e\u305f\u3081\u3001<\/p>\n<ul data-start=\"2018\" data-end=\"2040\">\n<li data-section-id=\"1ftfct\" data-start=\"2018\" data-end=\"2023\">\u30cb\u30ad\u30d3<\/li>\n<li data-section-id=\"yi95wz\" data-start=\"2024\" data-end=\"2028\">\u8d64\u307f<\/li>\n<li data-section-id=\"1gefxd\" data-start=\"2029\" data-end=\"2034\">\u304f\u3059\u307f<\/li>\n<li data-section-id=\"29m0d6\" data-start=\"2035\" data-end=\"2040\">\u808c\u75b2\u308c<\/li>\n<\/ul>\n<p data-start=\"2042\" data-end=\"2054\">\u304c\u60aa\u5316\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p data-start=\"2056\" data-end=\"2096\">\u73fe\u4ee3\u306e\u7f8e\u5bb9\u533b\u7642\u3067\u306f\u3001\u300c\u808c\u306f\u5168\u8eab\u72b6\u614b\u3092\u6620\u3059\u93e1\u300d\u3068\u8003\u3048\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb703d3 elementor-widget elementor-widget-image\" data-id=\"bb703d3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"212\" src=\"https:\/\/meelf.biz\/tpc\/wp-content\/uploads\/2026\/05\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-9-300x212.png\" class=\"attachment-medium size-medium wp-image-1971\" alt=\"\" srcset=\"https:\/\/meelf.biz\/tpc\/wp-content\/uploads\/2026\/05\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-9-300x212.png 300w, https:\/\/meelf.biz\/tpc\/wp-content\/uploads\/2026\/05\/\u6bb5\u843d\u30c6\u30ad\u30b9\u30c8-9-1024x724.png 1024w, 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